Thrombospondin type I repeat (TSR) domains are commonly O-fucosylated by protein O-fucosyltransferase 2 (PoFUT2), and this modification is required for optimal folding and secretion of TSR-containing proteins.The human malaria parasite Plasmodium falciparum expresses proteins containing TSR domains, such as the thrombospondin-related anonymous prot
Ruxolitinib is a cornerstone of management for some subsets of myeloproliferative neoplasms (MPNs); however, a considerable number of patients respond suboptimally.Here, we evaluated the efficacy of micheliolide (MCL), a natural guaianolide sesquiterpene lactone, alone or in combination with ruxolitinib in samples from patients with MPNs, JAK2V617F
The issuance of Law of the Republic of Indonesia No.6 of 2014 concerning Villages, positioning villages as the spearhead of national development.The existence of a village law also provides clarity about the position and the authority of the village government in managing village household affairs.The regulation also regulates government policies r
Rural women are particularly at risk of dying from breast cancer, because they Photo Frame do not take advantage of screening procedures that are readily available to their urban counterparts.The purpose of this non-experimental study was to explore characteristics of rural women who attended a free breast health program that included self breast e